Requisite(s): 91703 Physiological Systems AND 91313 Biomolecules: Structure and Function
This subject provides the introductory principles governing drug and xenobiotic action to be developed further in 91709 Pharmacology 2. It is designed to foster a problem-solving approach to pharmacology with particular emphasis on applying molecular pharmacology concepts to pathophysiological problems. Major objectives are to develop the concepts of dose response relationships and the specificity of drug action. Therapeutic index and the concept of selective toxicity. Chemical neurotransmitters, ion channels and receptors as determinants of drug action in the central and peripheral nervous systems. Clinical efficacy of the major pharmacology drug classes used in the treatment of pathophysiological processes involving the nervous systems. Lectures are complemented by a tutorial/practical program which emphasises the clinical nature of the subject and develops lecture material using a variety of experimental, tutorial, and computer-simulation approaches.
Autumn semester, City campus