91572 Proteomics

Description

Proteomics describes the study of the complete set of proteins (proteome) that is expressed at a given time in a cell, tissue, organ or organism. Modern proteomics involves the integration of a wide range of protein-analytical tools and information technologies to quickly and reliably identify qualitative and quantitative changes in proteins; for example, in the detection of altered protein expression associated with disease. This subject covers leading technologies for sample preparation, protein fractionations, separations and mass spectrometry for protein identification and characterisation.

Students explore facets of experimental design and data analysis through self-directed learning tasks and facilitated workshop activities. They are introduced to the best practice sample preparation technologies for different sample types, such as micro-organisms, plants, mammalian tissue and fluids. Written and oral assessment tasks require students to undertake independent research of relevant literature. The practical component allows students, through practice-related learning, to understand the logic and methodology underpinning sample preparation, complex mixture fractionation, protein separations and mass spectrometry. Students demonstrate their practice-related learning through the completion of a small laboratory-based project which requires a publication-style report encompassing data analysis skills.