91345 Biochemistry, Genes and Disease

This subject covers: biochemical and genetic aspects of human diseases for students planning careers in medical science, diagnostic biochemistry, molecular biology and biotechnology; calcium and bone disorders, such as osteoporosis; lipid metabolism and genotypes associated with familial hyperlipidaemia; assessment of thyroid and adrenal hormonal status using radioimmunoassay techniques; genetic basis of tests used to screen newborn infants for inborn errors of metabolism, e.g. phenylketonuria and cystic fibrosis, and for heritable diseases affecting adults such as haemaochromatosis (iron overload); scientific and social impacts of the human geonome project and discoveries of genotypes predisposing individuals to diseases such as bowel and breast cancer; current approaches to gene therapy for diabetes and other diseases; cancer chemotherapy and multi-drug resistance; and directed practicals and student project to evaluate test procedures used to detect and monitor the diseases covered.

Typical availability

Spring semester, City campus

Note(s)

This subject was formerly called Clinical Biochemistry 2.